Bettina Giersberg grew up in Potsdam and studied history at the Humboldt University in Berlin and at the Université Aix-Marseille. After completing her dissertation at the Centre for Research on Anti-Semitism at the Technical University of Berlin, she worked as a collection manager and exhibition curator in museums in Potsdam and Radebeul (near Dresden).
In 2014, she was part of the founding team of the "Ackerhus. Museum für Toggenburger Hauskultur" in Ebnat-Kappel (SG). As curator and director of the Museum des Landes Glarus in Näfels (GL), she was able to organise the exhibitions "Schön sitzen!", "Glarner Schätze", "Frau Hauptmannin und ihre Kinder. Portraits of the 17th Century" and "Fantastic Years. Haute Couture Fabrics from Mitlödi". Since 2023, she has been curator for Applied Art and Everyday Culture at the Historisches Museum Basel.
The mother of two adult children lives with her family in Basel.